Evaluation of therapy with cabergoline in men with macroprolactinoma

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Pneumocephalus during cabergoline treatment of an invasive macroprolactinoma.

A 43-year-old male trisomic patient was referred for acute left headache and progressive homolateral mydriasis and ptosis. Computed tomography and T2-magnetic resonance imaging demonstrated a 4 cm invasive pituitary adenoma (Panels A and C, respectively). Blood analyses revealed hyperprolactinemia (5460 ng/ml, normal values < 15 ng/ml) and severe gonadotrophic insuffi ciency. Treatment was clas...

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A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology

Pituitary adenomas are a common intracranial neoplasm, usually demonstrating a benign phenotype. They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and aggressive or nonaggressive. Prolactinomas account for 40-60% of all pituitary adenomas, with dopamine agonists representing the first-line treatment ...

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Cabergoline-Induced Pneumocephalus Following Treatment for Giant Invasive Macroprolactinoma Presenting With Spontaneous Cerebrospinal Fluid Rhinorrhea

Cerebrospinal fluid (CSF) rhinorrhea is rarely reported as the first presenting feature of giant invasive macroprolactinomas. Cerebrospinal fluid rhinorrhea is usually reported as a complication of trauma, neurosurgical, and skull-based procedures (such as pituitary surgery or radiations), and less frequently after medical treatment with dopamine agonists (DAs) for macroprolactinomas. This phen...

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ژورنال

عنوان ژورنال: Pomeranian Journal of Life Sciences

سال: 2016

ISSN: 2450-4637

DOI: 10.21164/pomjlifesci.95